Antimicrobial resistance of Escherichia coli isolated from chickens with Colibacillosis in and around Harare, Zimbabwe.
Loading...
Date
2012-11-14
Journal Title
Journal ISSN
Volume Title
Publisher
American Association of Avian Pathologists
Abstract
Colibacillosis, a disease caused by avian pathogenic Escherichia coli (APEC),can lead to great economic losses in the poultry industry. The aim of this study was to determine the prevalance of antibiotic resistance and antibiotic resistance and antibiotic resistance patterns in APEC in Zimbabwe. From 503 chickens diagnosed with Colibacillosis, 103 E. coli isolates were obtained. Isolation and identification of E. coli were carried out using microscopy and boichemical tests. The disc diffusion method was used to determine antibiotic susceptibility of the isolates to 8 commercial antibiotics. Many isolates exhibited resistance to more than one antibiotic. Antibiogram profiles indicated maximum resistance to tetracycline (100%), bacitracin(100%), and cloxacillin (100%) and a high prevalence of resistance to ampicillin(94.1%0. However; there were high prevalences of sensitivity to ciprofloxacin (100%) and gentamycin (97.1%). The isolates showed moderate rates of sensitivity to chloramphenicol and neomycin.All isolatesin this study showed multidrug resistance because they were all resistant to 3 or more antibiotics. Seven multidrug resistance patterns were observed. The most common pattern (resistance to ampicillin, bacitracin,cloxacillin and tetracycline) was exhibited by 30 isolates.Our findings show that there is emerging drug resistance in APEC associated with colibacillosis in Zimbabwe. The observed high level of multidrug resistance could hamper the treatment of colibacillosis in Zimbabwe.
Description
A case report.
Keywords
Escherichia coli, Colibacillosis, Antibiotic resistance, Zimbabwe, Poultry
Citation
Bamus, S., Mafirakureva, P. and Mbanga, J. (2012). Antimicrobial resistance of Escherichia coli isolated from chickens with Colibacillosis in and around Harare, Zimbabwe. American Association of Avian Pathologists.