Effect of schistosome infection on hepatic drug metabolising enzymes
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Date
1998-06
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
South African Journal of Science
Abstract
Schistosomiasis is a parasitic disease that affects over 200 million
persons worldwide.' The disease is caused by infection with
any one of several species that are known to affect humans.
Infected persons are likely to be consuming a wide spectrum of
xenobiotics such as drugs and environmental toxins. The drugs
consumed would not only include praziquantel and other schistosomicides,
but also those used for the treatment of other parasitic
diseases such as antimalarials, anthelmintics and antibiotics.
Experiments involving humans and experimental animals suggest
that infection with schistosomes causes a reduction in the
host's ability to metabolise and remove drugs from the body.
Description
Journal article from South African Journal of Science pages 301-302
Keywords
schistosome, hepatic, drug, enzymes
Citation
Naik, Yogeshkumar S. And Hasler, Julia A. (1996) Effect of schistosome infection on hepatic drug metabolising enzymes. South African Journal of Science.