Malaria Disease Perspective and an Opinion: Should Malaria Treatment Target the Parasite or the Malarial Pathophysiology Generated by the Parasite or Both?
dc.contributor.author | Mavondo, Greanious Alfred Alfrd | |
dc.date.accessioned | 2018-07-04T10:26:24Z | |
dc.date.accessioned | 2023-06-27T08:51:23Z | |
dc.date.available | 2018-07-04T10:26:24Z | |
dc.date.available | 2023-06-27T08:51:23Z | |
dc.date.issued | 2017-04-15 | |
dc.description | Journal article | en_US |
dc.description.abstract | The malaria disease is caused by primarily four protozoan microorganisms of the Plasmodium genus transmitted by the female Anopheles mosquito namely: P. falciparum, P. vivax, P. Malariae, P. ovalae. A fourth one, P. knowlesi is known natural pathogen of the marquis but can also infect human. With its ability to infect both mature and immature red blood cells (RBC’s), multiply rapidly, cause severe malaria anaemia (SMA), adhere to blood vessels endothelium, cause cerebral malaria, P. falciparum causes the most complications of the disease with high fatality rates. The most prevalent human malaria parasite is P. vivax with a propensity to relapse when dormant liver stages (hypnozoites) are activate to reinvade RBC’s many months to years after the initial malarial infection. The other parasites cause varying disease manifestation with less fatalities. | en_US |
dc.identifier.citation | Mavondo, G.A. 2017. Malaria Disease Perspective and an Opinion: Should Malaria Treatment Target the Parasite or the Malarial Pathophysiology Generated by the Parasite or Both?. EC MICROBIOLOGY. 7(5):149-154. | en_US |
dc.identifier.uri | https://www.researchgate.net | |
dc.identifier.uri | http://196.220.97.103:4000/handle/123456789/915 | |
dc.language.iso | en_US | en_US |
dc.publisher | EC MICROBIOLOGY | en_US |
dc.subject | malaria disease | en_US |
dc.subject | Malarial Pathophysiology | en_US |
dc.subject | Parasite | en_US |
dc.title | Malaria Disease Perspective and an Opinion: Should Malaria Treatment Target the Parasite or the Malarial Pathophysiology Generated by the Parasite or Both? | en_US |
dc.type | Article | en_US |
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